Early Diabetic Retinitis

Early Diabetic Nephropathy

OBJECTIVE Diabetic nephropathy (DN) is a major cause of mortality in type 1 diabetes. Reduced insulin sensitivity is a well-documented component of type 1 diabetes. We hypothesized that baseline insulin sensitivity would predict development of DN over 6 years. RESEARCH DESIGN AND METHODS We assessed the relationship between insulin sensitivity at baseline and development of early phenotypes o...

The early receptor potential in sex-linked retinitis pigmentosa.

An affected boy and two carrier women in a family with sex-linked retinitis pigmentosa have reduced early receptor potential (ERP) amplitudes compared to normals. The decrease in ERP amplitudes localizes a defect in the receptor outer segments. The ERP of the affected boy is reduced to less than 20 per cent of normal. This indicates that both receptor systems are involved in his degeneration. T...

IMPG2-associated retinitis pigmentosa displays relatively early macular involvement.

PURPOSE To provide the first detailed clinical description in patients with RP caused by recessive mutations in IMPG2. METHODS This international collaborative study includes 17 RP patients with inherited retinal disease caused by mutations in IMPG2. The patients were clinically (re-)examined, including extensive medical history taking, slit-lamp biomicroscopy, ophthalmoscopy, perimetry, ERG,...

Toxocaral chorio-retinitis. Treatment of early cases with photocoagulation.

Since Wilder (I950) described nematode endophthalmitis in patients previously diagnosed as cases of pseudoglioma, and Nichols (1956) identified the nematode as Toxocara canis, it has been recognized that this organism, which is very common in puppies all over the world, is liable to infect the human eye, particularly in young children. Ashton (I960) demonstrated the pathology of the condition. ...

Aids Presenting Early Cytomegalovirus Retinitis – a Case Report